Sunday, June 14, 2020

Risk: Science, Statistics, and the Unknown


Parable

There once was a Gentleman Farmer who watched over a flock of hens. On most mornings, he enjoyed a couple of deliciously fresh eggs from his flock.  The GF believed that allowing the flock to roam free around the property was good for the health of the flock and probably added to the richness of the taste of the eggs.  But, alas, there was a problem. A fox had been sighted near the farm, and personal experience had taught him that within a very brief period of time, a fox could devastate the flock. Yet in a six-year period of time, during which the flock had been allowed to roam free only 40% of the time, a fox had plundered the flock only one time.  Could the farmer take that risk with his precious flock?



Science and COVID-19

Science is defined as, “the intellectual and practical activity encompassing the systematic study of the structure and behavior of the physical and natural world through observation and experiment.” 

COVID-19 is a disease caused by a specific coronavirus labeled SARS-CoV-2.

According to the U.S. Centers for Disease Control and Prevention (CDC), there are actually multiple types of coronaviruses, some of which commonly cause mild upper-respiratory tract illnesses. There are seven types of coronavirus that infect humans, three of which evolved from animal strains. 
Because there are many coronavirus types, referring to it simply as "coronavirus" is very general. The CDC and World Health Organization (WHO) encourage experts to use COVID-19 when referring to this new disease, a novel (or new) coronavirus that has not previously been seen in humans. In COVID-19, ‘CO’ stands for ‘corona,’ ‘VI’ for ‘virus,’ ‘D’ for disease and 19 indicates the year it was discovered. 
Just as the general public has become familiar with this terminology, officials have also begun using SARS-CoV-2 in connection with the recent outbreak. Severe acute respiratory syndrome coronavirus 2, shortened to SARS-CoV-2, is actually the virus that causes COVID-19 (the disease). As the name indicates, this virus is genetically related to the SARS-associated coronavirus (SARS-CoV) that caused an outbreak of severe acute respiratory syndrome (SARS) in 2002-2003, however it is not the same virus.

Scientists believe that SARS-CoV-2 originated in horseshoe bats.  Although humans could have caught the deadly virus directly from bats, there is strong evidence that suggests that pangolins may have been an intermediate host.  A pangolin looks like a reptile, but is actually a mammal.  They are one of the most trafficked mammals in Asia and, increasingly, Africa. Pangolins are in high demand in countries like China and Vietnam. Their meat is considered a delicacy and pangolin scales are used in traditional medicine and folk remedies. All eight pangolin species are protected under national and international laws. But there is still growing international illegal trade in pangolins.  It is estimated that the industry that sells exotic wildlife in burgeoning wildlife markets is worth $76 billion dollars.


 Statistics

As of 6/11/20, there have been more than 2 million confirmed cases of COVID-19 in the US and 112,000 confirmed deaths. When trying to assess risk of death, one must first do the math: 112,000 divided by 2,000,000 = 5.6%.  The first death from COVID-19 in the US happened in early February, 2020.

Let’s try to place this number in a broader context by looking at other annual mortality numbers in the US.

Coronary heart disease                                                375,000
Lung diseases                                                        296,000
Brain diseases (stroke and Alsheimer’s)   214,000
Digestive cancers                                                            106,000
Infections (respiratory and blood)             95,000
Suicide                                                                     41,000
Automobile accidents in 2018                      36,560

(the above data came from How Not To Die, by Michael Greger and Gene Stone, pg. 10 and 11)

The Unknown

How does a person in a vulnerable age group remain disease free?  We know that the disease is highly contagious; therefore, keeping a safe distance from an infected person seems paramount. If a person feels sick, they should STAY HOME, but a semi-controlled study out of Iceland shows that around 50% of those who tested positive were determined to be asymptomatic for COVID-19 and thus have played an important role in spreading the disease.  Those individuals would not have stayed home because they never knew they were contagious.



RISK

Determining a statistical equation that provides us a roadmap for staying free from COVID-19 is a near impossibility, therefore, we must assume that every person with whom we come into close contact is infected with the disease.  We must pin our hopes on two important factors: 1) that a vaccine is found sooner than later; and 2) if we are infected, the disease will not specifically be lethal to us.

Double, double toil and trouble,
Should we live life in a bubble?

Life is precious, and for me the answer to that question, for now, is YES.

This farmer will work to keep the fox from the hen house!


CPW

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